• # LGM Pharma is a Mupirocin CAS# 12650-69-0 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
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  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Mupirocin
  • CAS #: 12650-69-0
  • Mode of Action:

    Mupirocin reversibly binds to bacterial isoleucyl-tRNA synthetase, an enzyme which promotes the conversion of isoleucine and tRNA to isoleucyl-tRNA. Prevention of this enzymes from functioning properly results in the inhibition of bacterial protein and RNA synthesis.

  • Pharmacodynamics:

    Mupirocin, an antibiotic produced from Pseudomonas fluorescens, is structurally unrelated to any other topical or systemic antibiotics. Mupirocin is used to treat infection caused by Staphylococcus aureus and beta-hemolytic streptococci including Streptococcus pyogenes. This antibiotic has little, if any, potential for cross-resistance with other antibiotics.

  • Metabolism:

    Hepatic. Following intravenous or oral administration, mupirocin is rapidly metabolized. The principal metabolite is monic acid, which has no antibacterial activity.

  • IUPAC: 9-{[(2E)-4-[(2S, 3R, 4R, 5S)-3, 4-dihydroxy-5-{[(2S, 3S)-3-[(2S, 3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl}oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid
  • ATC: D06AX09 R01AX06
  • PubChem: 446596
  • DrugBank: DB00410 (APRD00162)
  • Formula: C21H21N
  • Molecular Mass: 500.6222
  • Synonyms: MRC Mupirocine Pseudomonic acid
  • SMILES: C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]1CO[C@@H](CC(C)=CC(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O
  • AHFS Code: 24:04.0
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