• # LGM Pharma is a Goserelin Acetate CAS# 145781-92-6 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
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  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Goserelin Acetate
  • CAS #: 145781-92-6
  • Mode of Action:

    Goserelin is a synthetic decapeptide analogue of LHRH. Goserelin acts as a potent inhibitor of pituitary gonadotropin secretion when administered in the biodegradable formulation. The result is sustained suppression of LH and serum testosterone levels.

  • Pharmacodynamics:

    The pharmacokinetics of goserelin have been determined in both male and female healthy volunteers and patients. In these studies, goserelin was administered as a single 250µg (aqueous solution) dose and as a single or multiple 3.6 mg depot dose by subcutaneous route.

  • Metabolism:


  • Toxicity:

    No experience of overdosage from clinical trials.

  • IUPAC: 1-9-Luteinizing hormone-releasing factor (swine), 6-(O-(1, 1-dimethylethyl)-D-serine)-, 2-(aminocarbonyl)hydrazide, acetate (salt)
  • ATC: L02AE03
  • PubChem: 5311128
  • DrugBank: BTD00113
  • Formula: C59-H84-N18-O14.x-C2-H4-O2
  • Molecular Mass: 1329.4762
  • SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NNC(=O)N)NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4c3cccc4)NC(=O)[C@H](Cc5c[nH]cn5)NC(=O)[C@@H]6CCC(=O)N6.CC(=O)O
  • AHFS Code: 68:18.00, 92:00.00
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