• # LGM Pharma is a Cefprozil CAS# 92665-29-7 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
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  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Cefprozil
  • CAS #: 92665-29-7
  • Mode of Action:

    Cefprozil, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefprozil interferes with an autolysin inhibitor.

  • Pharmacodynamics:

    Cefprozil, a semisynthetic, second-generation cephalosporin, is used to treat otitis media, soft-tissue infections, and respiratory tract infections.

  • Metabolism:

    Cefprozil is eliminated primarily by the kidneys

  • Toxicity:

    Single 5000 mg/kg oral doses of cefprozil caused no mortality or signs of toxicity in adult, weaning or neonatal rats, or adult mice. A single oral dose of 3000 mg/kg caused diarrhea and loss of appetite in cynomolgus monkeys, but no mortality.

  • IUPAC: (6R, 7R)-7-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-8-oxo-3-(prop-1-en-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • ATC: J01DC10
  • PubChem: 9887643
  • DrugBank: DB01150 (APRD00461)
  • Formula: C26H28N2
  • Molecular Mass: 389.426
  • Synonyms: Cefprozil anhydrous Cefprozilo [INN-Spanish] Cefprozilum [INN-Latin]
  • SMILES: [H][C@]12SCC(C=CC)=C(N1C(=O)[C@@]2([H])NC(=O)[C@H](N)C1=CC=C(O)C=C1)C(O)=O
  • AHFS Code: 08:12.06.08
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