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Bromfenac sodium

 

  • # LGM Pharma is a Bromfenac sodium CAS# 91714-93-1 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
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  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Bromfenac sodium
  • CAS #: 91714-93-1
  • Mode of Action:

    The mechanism of its action is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. Prostaglandins have been shown in many animal models to be mediators of certain kinds of intraocular inflammation. In studies performed in animal eyes, prostaglandins have been shown to produce disruption of the blood-aqueous humor barrier, vasodilation, increased vascular permeability, leukocytosis, and increased intraocular pressure.

  • Pharmacodynamics:

    Bromfenac ophthalmic solution is a sterile, topical, nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use.

  • IUPAC: Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-, monosodium salt
  • ATC: S01BC11
  • DrugBank: DB00963
  • Formula: C15-H12-Br-N-O3.Na
  • Molecular Mass: 356.1499
  • Synonyms: AHR 10282B, Bromfenac sodium, Bromsite, Bronuck, UNII-9X8YF771OU
  • SMILES: c1cc(c(c(c1)C(=O)c2ccc(cc2)Br)N)CC(=O)[O-].[Na+]
  • InChl: 1S/C15H12BrNO3.Na/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;/h1-7H,8,17H2,(H,18,19);/q;+1/p-1
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