59338-93-1 Category:
  • # LGM Pharma is a Alizapride CAS# 59338-93-1 API supplier distributor based in the USA. Inquire about DMF, cGMP, price, availability, samples, sourcing, purity and more.
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  • # LGM Pharma offers this active ingredient but not the finished dosage forms.
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Product Details:

  • Product Name: Alizapride
  • CAS #: 59338-93-1
  • Mode of Action:

    The anti-emetic action of Alizapride is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone (CTZ) in the central nervous system (CNS)ãthis action prevents nausea and vomiting triggered by most stimuli. Structurally similar to metoclopramide and, therefore, shares similar other atributres related to emesis and prokinetics.

  • Pharmacodynamics:

    Alizapride is a dopamine antagonist.

  • IUPAC: 6-methoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-2H-1, 2, 3-benzotriazole-5-carboxamide
  • ATC: A03FA05
  • PubChem: 43008
  • DrugBank: DB01425
  • Formula: C21H19N3O3S
  • Molecular Mass: 315.3702
  • Synonyms: Alizaprida [inn-spanish] Alizapridum [inn-latin]
  • General Reference:

    1. Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20. Pubmed

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