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Crizotinib


Phase 1 clinical trial results for Ceritinib have revealed affirmative results, leading the FDA to grant an accelerated approval for this impressive drug. Deemed to be “highly active” in the fight against ALK-rearranged non-small-cell lung cancer, Ceritinib is also twenty times more potent than Crizotinib. The exciting results from Novartis’s Phase 1 trial were recently[…]

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On November 21, 2013 the FDA announced the approval of the formidable cancer drug Crizotinib to treat ALK-positive tumors. Patients with metastatic non-small cell lung cancer who have anaplastic lymphoma kinase (ALK)-positive tumors stand to benefit greatly from the Crizotinib FDA approval.  Encouraging data that demonstrated efficacious progression-free survival propelled the Crizotinib FDA approval decision. In 2011[…]

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Crizotinib, CAS number 877399-52-5, is also known as the brand Xalkori. Xalkori, manufactured Pfizer, was approved on August 26, 2011 by the FDA for metastatic non-small cell lung cancer. Crizotinib is ideal for patients who have a certain type of chromosome translocation, specifically one that affects the anaplastic lymphoma kinase, or ALK gene, which causes[…]

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