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Drug Research & Development API


Naltrexone is typically administered to those who have a history of substance abuse, namely opiates or alcohol. The drug works to block the intensity of the drugs, so people are less likely to associate them with euphoria or pain relief. Because drug use in this country is still so stigmatized, it’s difficult to separate public[…]

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Fingolimod Hydrochloride blog

Fingolimod Hydrochloride CAS: 162359-56-0 Fingolimod Hydrochloride is typically given to those who suffer from multiple sclerosis (MS) relapses. It doesn’t eliminate episodes in the body entirely, but it can reduce them by 50% or more over the course of several years. When the body is having an autoimmune reaction, the lymphocytes play a big role[…]

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Amphotericin B

Amphotericin B: CAS No: 1397-89-3 Amphotericin B is an API used to treat a number of fungal infections. This pharmaceutical ingredient is aggressive when interacting with the fungus which is why it’s generally used for serious cases only. However, it’s also proven itself to be one of the most effective ways to stop the spread[…]

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Sitagliptin Phosphate

Sitagliptin Phosphate CAS No: 654671-78-0 Sitagliptin Phosphate was approved more than a decade ago primarily as a way to combat type 2 diabetes. This dipeptidyl-peptidase-4 inhibitor lowers the levels of glucose in the patient directly following a meal and can also help regulate general blood sugar levels over time. It’s usually used in combination with[…]

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Brimonidine Tartrate

Brimonidine Tartrate CAS No: 79570-19-7 Known for treating open-angle glaucoma, brimonidine tartrate is a safe and effective API for reducing pressure behind the eye. The medication allows better drainage of fluids to both relieve patient suffering and protect eyes from further damage. High-fluid pressure can cause anything from mild nerve damage to total blindness. However,[…]

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Chemical entities SHINE in the top 10 fastest-growing drugs of 2016

This week, PharmaCompass continued its analysis of the top 10 fastest-growing drugs of 2016 by sales to evaluate the drugs that registered large sales growth. Please note that these are not the top-selling drugs, but are the top 10 drugs that registered the maximum growth in global sales over 2015. Interestingly, things didn’t appear that[…]

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Eteplirsen CAS 1173755-55-9

The U.S. Food and Drug Administration approved Eteplirsen CAS# 1173755-55-9 (marketed as Exondys 51) injection, the first drug approved to treat patients with Duchenne muscular dystrophy (DMD). Exondys 51 is specifically indicated for patients who have a confirmed mutation of the dystrophin gene amenable to exon 51 skipping, which affects about 13 percent of the[…]

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The Threat of Antibiotic Resistance

Biapenem CAS No: 120410-24-4 Doripenem CAS No: 148016-81-3 Ertapenem CAS No: 153832-46-3 Imipenem CAS No: 74431-23-5 Meropenem CAS No: 96036-03-2 Panipenem CAS No: 87726-17-8 A new publication is out called “May 19, 2016 – Tackling Drug-Resistant Infections Globally: final report and recommendations” and it highlights the antibiotic-resistant infections which are being seen for the 1st[…]

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Osteoporosis, Paget’s Disease and Alendronate As part of the of drug family called bisphosphonates alendronate sodium works by increasing the thickness of bone by slowing down the cells that usually break down bone. This allows the cells that build bone to work more efficiently. Alendronate can help to reduce the incidence of osteoporosis-related fractures by[…]

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Acamprosate

The drug Acamprosate, sold as Campral®, is used (in combination with counseling) to help people recovering from alcoholism to avoid drinking alcohol again. It reduces alcohol consumption in animal models of alcohol addiction. When a person has been drinking large amounts of alcohol for a long time, it changes the way their brain works. The[…]

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