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Donepezil, CAS number 120014-06-4, is also marketed under the brand name Aricept, and is used in treatment of Alzheimer’s disease. Patients with dementia have low levels of the brain chemical acetylcholine, which is a crucial chemical for thinking and memory issues. Donepezil improves the patient’s nerve cell functioning by inhibiting the breakdown of acetylcholine. Aricept,[…]

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Tacrolimus, CAS number 104987-11-3, was the second macrolide immunosuppressant discovered, second only to discovery of rapamycin (sirolimus) on Rapa Nui (Easter Island) in 1975. Discovered in 1984, tacrolimus, also known as FK-506 or Fujimycin, is an immunosuppressant drug, often given to organ transplant recipients. Tacrolimus is effective in helping to prevent transplant patients from experiencing[…]

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Risperidone is sold under the brand name Risperdal in the United States. First developed by Janssen-Cilag, risperidone is an atypical antipsychotic that was initially released in 1994. Risperdal (risperidone) is used for patients suffering from adolescent and adult schizophrenia, schizoaffective disorder, and manic states of bipolar disorder. The FDA approved risperidone in 2003 for short[…]

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In developed nations, between 20-40 percent of adults experience heartburn on a regular basis. Heartburn is characterized by a burning sensation that rises from the stomach towards the chest and neck. It has often been mistaken as angina, a symptom of heart attack. Heartburn is the primary symptom of gastroesophageal reflux disease (GERD). When left[…]

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Gonorrhea is a sexually transmitted disease (STD) caused by the bacterium Neisseria Gonorrhoeae. Gonorrhea is a very common infectious disease among the sexually active young adults and teens. The Center for Disease Control and Prevention (CDC) estimates that more than 700,000 persons in the U.S. acquire the infection yearly. Unlike HIV, exchange of body fluids[…]

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A recent study conducted by the Queens University Belfasts School of Pharmacy revealed the ability of the recombinant protein FKBPL to inhibit tumor growth by disrupting the blood supply to these tumors. This method of cancer treatment called neovascularization is certainly not new with several agents exhibiting the same mode of action already available in[…]

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Anti-diabetic drugs treat diabetes by lowering glucose levels in the blood. One class of anti-diabetic drugs that are used in the management of diabetes is Sulfonylurea. Sulfonylurea derivatives are used in the management of diabetes mellitus type 2.  They act by increasing insulin release from the beta cells in the pancreas.  Diabetes mellitus type 2[…]

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