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Antithrombotic


The FDA exclusivity for Plavix (clopidogrel) ended on May 17, 2012, while patent protection expires January 31, 2014. This exciting news brings Clopidogrel CAS# 113665-84-2, to the forefront of pharmaceutical news. With sales of Plavix generating billions of dollars for Bristol-Myers Squibb/Sanofi Pharmaceuticals, researchers are clamoring to create generic options of clopidogrel. As an antiplatelet[…]

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Apixaban, CAS number 503612-47-3, is showing itself to be a viable option for patients with atrial fibrillation who are in need of an anticoagulant. In two studies, ARISTOTLE and AVERROES, which included over 24,000 patients, Apixaban (Eliquis) showed statistically significant superiority to Warfarin.  A 21%  lower stroke risk for patients with atrial fibrillation was an[…]

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Stroke is the leading cause of neurologic disability in the US and Europe among adults. Worldwide, it is the second leading cause of death, trailing after coronary artery disease (CAD) in developed nations. In an ischemic stroke, the patient’s blood supply to certain parts of the brain is decreased, resulting to loss of function in[…]

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Patients with pulmonary hypertension can look at Treprostinil and breathe a sigh of relief. For years, this type of hypertension has been managed by a limited choice of treatment options such as oxygen, vasodilators and prostaglandins. These two treatment options are used to “open up” the arteries which results in reduced pressure in the blood[…]

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In a world where about a third of the adult male in the global population smokes, it’s tough not to take notice of its negative impact on the society as a whole. According to the WHO, if the smoking trends do not ease up, one in every 6 adults will die of smoking-related illness (e.g.[…]

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What Are Monoclonal Antibodies? A monoclonal antibody is a laboratory-produced molecule that’s carefully engineered to attach to specific defects in your cancer cells. Monoclonal antibodies mimic the antibodies your body naturally produces as part of your immune system’s response to germs, vaccines and other invaders.   Growing Interest for Monoclonal Antibody Therapies Monoclonal antibodies were initially[…]

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