Plicamycin 18378-89-7
Plicamycin (INN, also known as mithramycin; trade name Mithracin) is an antineoplastic antibiotic produced by Streptomyces plicatus.
Uses
It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. It has been tested in chronic myeloid leukemia.
| Systematic (IUPAC) name: | (1S)-5-deoxy-1-C-((2S,3S)-7-{[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy}-3-{[2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy}-5,10-dihydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)-1-O-methyl-D-xylulose |
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| Plicamycin CAS number: | 18378-89-7 |
| ATC code: | L01DC02 |
| PubChem: | 29051 |
| DrugBank: | |
| Formula: | C52H76O24 |
| Molecular mass: | 1085.15 g/mol |
| Plicamycin Assay/Purity: | Typically NLT 98% |
