Mevastatin 73573-88-3
Mevastatin, compactin, ML-236B is a hypolipidemic agent that belongs to the statins class. It was the first compound isolated in the 70s during research into HMG-CoA reductase inhibitors produced by a mould Penicillium citrinum. Mevastatin is not used in therapy of hyperlipidemias because of multiple side effects but it is the only source for production of another statin - pravastatin. In vitro it has antiproliferative properties. High doses inhibit growth and proliferation of melanoma cells.
read more [+]| Systematic (IUPAC) name: | (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate |
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| Mevastatin CAS number: | 73573-88-3 |
| ATC code: | |
| PubChem: | 64715 |
| DrugBank: | |
| Formula: | C23H34O5 |
| Molecular mass: | 408.534 g/mol |
| Mevastatin Assay/Purity: | Typically NLT 98% |
