Benfluorex 23602-78-0

Benfluorex

Benfluorex is an anorectic and hypolipidemic agent. Clinical studies have shown it may improve glycemic control and decrease insulin resistance in people with poorly controlled type 2 diabetes; it is marketed in France as an adjuvant antidiabetic. On 18 December 2009 the European Medicines Agency (EMEA) has recommended the withdrawal of all medicines containing benfluorex in the European Union, because their risks, particularly the risk of heart valve disease (fenfluramine-like cardiovascular side-effects), are greater than their benefits. Benfluorex is structurally related to fenfluramine.

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Systematic (IUPAC) name: (RS)-2-({1-[3-(trifluoromethyl)phenyl]propan- 2-yl}amino)ethyl benzoate
Benfluorex CAS number: 23602-78-0
ATC code: A10BX06
PubChem: 2318
DrugBank:
Formula: C19H20N1O2
Molecular mass: 351.363 g/mol
Benfluorex Assay/Purity: Typically NLT 98%
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