Amprenavir 161814-49-9

Amprenavir Amprenavir (Agenerase, GlaxoSmithKline) is a protease inhibitor used to treat HIV infection. It was approved by the Food and Drug Administration on April 15, 1999, for twice-a-day dosing instead of needing to be taken every eight hours. The convenient dosing came at a price, as the dose required is 1,200mg, delivered in eight very large gel capsules.

Systematic (IUPAC) name: (3S)-oxolan-3-ylN-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)(4-aminobenzene)sulfonamido]-1-phenylbutan-2-yl]carbamate
Amprenavir CAS number: 161814-49-9
ATC code: J05AE05
PubChem: 65016
DrugBank: APRD00605
Formula: C25H35N3O6S
Molecular mass: 505.628 g/mol
Amprenavir Assay/Purity: Typically NLT 98%
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