Olopatadine 113806-05-6
Olopatadine hydrochloride is an antihistamine (as well as anticholinergic) and mast cell stabilizer, sold as a prescription eye drop (0. 2% solution, Pataday (or Patanol S in some countries), manufactured by Alcon). It is used to treat itching associated with allergic conjunctivitis (eye allergies). Olopatadine hydrochloride 0. 1% is sold as Patanol (or Opatanol in some countries). A nasal spray formulation is sold as Patanase, which was approved by the FDA on April 15, 2008. It is also available as an oral tablet in Japan under the tradename Allelock, manufactured by Kyowa Hakko Kogyo. It should not be used to treat irritation caused by contact lenses. The usual dose for Pataday is 1 drop in each affected eye once a day. The usual dose for Patanol is 1 drop in each affected eye 2 times per day, with 6 to 8 hours between doses. Its side effects may include headaches (7% of occurrence) burning and stinging (5%), dry eye, foreign body sensation, hyperemia, keratitis, lid edema, pruritus, asthenia, cold syndrome, pharyngitis, rhinitis, sinusitis, and taste perversion. Olopatadine was developed by Kyowa Hakko Kogyo.
read more [+]| Systematic (IUPAC) name: | {(11Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid |
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| Olopatadine CAS number: | 113806-05-6 |
| ATC code: | S01GX09 R01AC08 |
| PubChem: | 5281071 |
| DrugBank: | APRD00310 |
| Formula: | C21 H23 N1 O3 |
| Molecular mass: | 337.412 [[Gram g/mol |
| Olopatadine Assay/Purity: | Typically NLT 98% |
