Edaravone 89-25-8

Edaravone

Edaravone (Radicut) is a neuroprotective agent used for the purpose of aiding neurological recovery following acute brain ischemia and subsequent cerebral infarction. It acts as a potent antioxidant and strongly scavenges free radicals, protecting against oxidative stress and neuronal apoptosis. It has been marketed solely in Japan by Mitsubishi Pharma since 2001. Edaravone has been shown to attenuate methamphetamine- and 6-OHDA-induced dopaminergic neurotoxicity in the striatum and substantia nigra, and does not affect methamphetamine-induced dopamine release or hyperthermia.

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Systematic (IUPAC) name: 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
Edaravone CAS number: 89-25-8
ATC code:
PubChem: 4021
DrugBank:
Formula: C10H10N2O1
Molecular mass: 174.20 g/mol
Edaravone Assay/Purity: Typically NLT 98%
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