Acetohexamide

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Acetohexamide

Acetohexamide (trade name Dymelor) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.

Mechanism of action

Acetohexamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. For this reason, acetohexamide is not used to treat diabetes mellitus type 1.

Risks

Oral hypoglycemic drugs, including acetohexamide, have been associated with increased cardiovascular mortality. Talk to your doctor about the possible risks, benefits, and alternatives of using this drug for your condition.

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Systematic (IUPAC) name 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide
CAS number 968-81-0
ATC code A10BB31
PubChem 1989
DrugBank APRD00773
Formula: C15H20N2O4
Molecular mass 324.395 g/mol
Assay/Purity Typically NLT 98%
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