Acemetacin

Acemetacin

Acemetacin is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. It is manufactured by Merck under the tradename Emflex, and is available in the UK as a prescription-only drug. Acemetacin, a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of acemetacin is that it reduces gastric damage when compared to indometacin. {{Anti-inflammatory and antirheumatic products

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Systematic (IUPAC) name 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid
CAS number 53164-05-9
ATC code M01AB11
PubChem 1981
DrugBank
Formula: C21H18N1O6
Molecular mass 415.82372 g/mol
Assay/Purity Typically NLT 98%
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