As an effectual antiviral drug, Famciclovir, CAS number 104227-87-4, is a key treatment for infections caused by the herpes virus. Novartis holds the patent for Famvir, which is the brand name for famciclovir, but that is expiring on September 1, 2015. While famciclovir is not a cure for herpes, it will slow the growth and spread of the herpes virus so that the body can fight off the infection. Famvir is efficacious at treating several types of infections caused by the herpes virus, including genital herpes, cold sores, and shingles.
According to the CDC almost 1 out of every 3 people in the United States will develop shingles, also known as zoster or herpes zoster. There are an estimated 1 million cases each year in the United States. Many myths surround shingles, and how one can contract it, but the CDC reports that anyone who has recovered from chickenpox may develop shingles, including children. The risk of disease increases as people age, and about half of all cases occur among men and women 60 years of age and older. Shingles is caused by the varicella zoster virus, the same virus that causes chickenpox. Upon recovery from the chickenpox, the virus lies dormant in the body in an inactive state. Scientists have not yet pinpointed the exact reason why this occurs, but some people experience a reactivation of the virus, thus causing shingles. This is not the same form of herpes which causes genital herpes, which is a sexually transmitted disease.
Patients allergic to famciclovir or penciclovir cream (Denavir) should not take famciclovir. Treatment is most effectual when started at the first signs of shingles, such as tingling, burning and blistering of the skin. Side effects from famciclovir include stomach pain, gas, nausea, diarrhea, exhaustion, dizziness, headache, itching and numbness.
Famciclovir may also be used to treat patients with repeat outbreaks of herpes virus cold sores or fever blisters in people with a normal immune system. People with repeat outbreaks of genital herpes, or as a prevention of anticipated outbreaks will also find relief from treatment with famciclovir. Available as a tablet to be taken orally, either with or without food, famciclovir is typically dosed at 500 milligrams three times daily for one week for those patients with shingles. Those patients suffering from a genital herpes outbreak should receive 1000 milligrams, to be taken twice for one day. However, if used for the prevention of future outbreaks of genital herpes, famciclovir should be taken twice a day, 250 milligrams each dose, for up to one year. In the treatment of cold sores famciclovir is effective as a single dose of 1500 milligrams. LGM Pharma offers the API famciclovir, as well as the TEVA API famciclovir. LGM Pharma is proud to be a Sole Distributor of Teva for their extensive API portfolio, for the US pharmacy compounding market.
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