Archive for the ‘Glossary’ Category

Prostaglandins: What are they and how do they work?

Wednesday, July 13th, 2011

ProstaglandinA prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring.

They are mediators and have a variety of strong physiological effects, such as regulating the contraction and relaxation of smooth muscle tissue. Prostaglandins are not hormones, but autocrine or paracrine, which are locally acting messenger molecules. They differ from hormones in that they are not produced at a discrete site but in many places throughout the human body. Also, their target cells are present in the immediate vicinity of the site of their secretion (of which there are many).

The prostaglandins, together with the thromboxanes and prostacyclins, form the prostanoid class of fatty acid derivatives, a subclass of eicosanoids.

Looking to buy prostaglandin products for research and development purposes? See LGM Pharma’s Prostaglandin products listed below:

Product Name: CAS#:
Alfaprostol 74176-31-1
Alprostadil  745-65-3
Beraprost Sodium 88475-69-8
Bimatoprost 155206-00-1
Carboprost 35700-23-3
Carboprost Tromethamine 58551-69-2
Cloprostenol 40665-92-7
Cloprostenol Sodium 55028-72-3
Dinoprost Tromethamine Salt 38562-01-5
Dinoprost  551-11-1
Dinoprostone 363-24-6
Epoprostenol Sodium 61849-14-7
Iloprost 73873-87-7
Latanoprost 130209-82-4
Limaprost Alfadex 88852-12-4
Lubiprostone 136790-76-6
Luprostiol 67110-79-6
Misoprostol 59122-46-2
Tafluprost 209860-87-7
Tiaprost 71116-82-0
Travoprost 157283-68-6
Treprostinil Sodium 289480-64-4
Unoprostone 120373-36-6
Unoprostone Isopropyl Ester 120373-24-2
Prostaglandin intermediates :
D-Corey lactone 76704-05-7
L-Corey lactone 32233-40-2
Corey Lactone 4-Phenylbenzoate 31752-99-5
Corey Lactone Benzoate 39746-00-4
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1).
Any patent infringement and resulting liability is solely at buyer risk.

TAPI (TEVA Active Pharmaceutical Ingredients)

Thursday, August 12th, 2010

TAPI (Teva Active Pharmaceutical Ingredients)

TAPI is an international supplier of active pharmaceutical ingredients, with more than $1.9 Billion in annual sales. TAPI employs over 4,600 professionals worldwide and boasts a portfolio of over 290 active pharmaceutical ingredients.  TAPI is a stand alone business unit within Teva Pharmaceutical Industries Limited and as its mother company is headquartered in Israel.  TAPI’s customers are leading generic & innovative pharmaceutical manufacturers.

Teva API division (TAPI) manufactures over 315 different API’s covering various therapeutic categories, and have registered 226 US-DMF’s as well as 83 EDQM COS’s up till date. TAPI group factories include well known names in the global pharmaceutical landscape, such as:

  • IVAX (Czech Republic)
  • Sicor (Italy, Mexico)
  • Pliva (Croatia)
  • TPW Biogal (Hungary)
  • PFC (Italy)

All the TAPI group factories are fully regulated and approved by global regulatory authorizations such as the US-FDA, MHRA and others.

LGM and TAPI

LGM and TAPIIn continuation with our efforts to bring only the finest quality API’s to our clients while minimizing any regulatory problems and quality issues, we are delighted to inform you that our company LGM Pharma has now been selected as the Sole Distributor of Teva for their extensive API portfolio, for the US pharmacy compounding market.

TAPI are widely recognized as the world-leader in terms of their API production, excellent GMP quality assurance and extensive regulatory position. We at LGM Pharma are proud to be able to bring to you all of these advantages!

Please do not hesitate to contact us for any API’s that are produced by any of the TAPI group factories – Teva, IVAX, Sicor, Pliva and others, and we will be glad to be in touch for any price quotations that may be required.

View our TAPI products, our agency appointment letter, and our TAPI Products PDF.

 

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1).  Any patent infringement and resulting liability is solely at buyer risk.