Wednesday, July 13th, 2011
A prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring.
They are mediators and have a variety of strong physiological effects, such as regulating the contraction and relaxation of smooth muscle tissue. Prostaglandins are not hormones, but autocrine or paracrine, which are locally acting messenger molecules. They differ from hormones in that they are not produced at a discrete site but in many places throughout the human body. Also, their target cells are present in the immediate vicinity of the site of their secretion (of which there are many).
The prostaglandins, together with the thromboxanes and prostacyclins, form the prostanoid class of fatty acid derivatives, a subclass of eicosanoids.
Looking to buy prostaglandin products for research and development purposes? See LGM Pharma’s Prostaglandin products listed below:
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Posted in Glossary, Prostaglandin, Therapeutic Classification | 1 Comment »
Thursday, August 12th, 2010
TAPI (Teva Active Pharmaceutical Ingredients)
TAPI is an international supplier of active pharmaceutical ingredients, with more than $1.9 Billion in annual sales. TAPI employs over 4,600 professionals worldwide and boasts a portfolio of over 290 active pharmaceutical ingredients. TAPI is a stand alone business unit within Teva Pharmaceutical Industries Limited and as its mother company is headquartered in Israel. TAPI’s customers are leading generic & innovative pharmaceutical manufacturers.
Teva API division (TAPI) manufactures over 315 different API’s covering various therapeutic categories, and have registered 226 US-DMF’s as well as 83 EDQM COS’s up till date. TAPI group factories include well known names in the global pharmaceutical landscape, such as:
- IVAX (Czech Republic)
- Sicor (Italy, Mexico)
- Pliva (Croatia)
- TPW Biogal (Hungary)
- PFC (Italy)
All the TAPI group factories are fully regulated and approved by global regulatory authorizations such as the US-FDA, MHRA and others.
LGM and TAPI
In continuation with our efforts to bring only the finest quality API’s to our clients while minimizing any regulatory problems and quality issues, we are delighted to inform you that our company LGM Pharma has now been selected as the Sole Distributor of Teva for their extensive API portfolio, for the US pharmacy compounding market.
TAPI are widely recognized as the world-leader in terms of their API production, excellent GMP quality assurance and extensive regulatory position. We at LGM Pharma are proud to be able to bring to you all of these advantages!
Please do not hesitate to contact us for any API’s that are produced by any of the TAPI group factories – Teva, IVAX, Sicor, Pliva and others, and we will be glad to be in touch for any price quotations that may be required.
View our TAPI products, our agency appointment letter, and our TAPI Products PDF.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271(e)+A13(1). Any patent infringement and resulting liability is solely at buyer risk.
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Posted in Glossary, TAPI Product, TEVA API | 1 Comment »
Thursday, August 12th, 2010
Active pharmaceutical ingredients (API) are chemicals used in the manufacturing of drugs. APIs include substances manufactured by processes such as (1) chemical synthesis; (2) fermentation; (3) recombinant DNA or other biotechnology methods; (4) isolation/recovery from natural sources; or (5) any combination of these processes. Similar terms include bulk active and bulk drug substance, although API is more internationally recognized.
An active ingredient (AI) is the substance or mixture of substances in a pharmaceutical drug that is biologically active. The active ingredient is the product component responsible for an effect the product was designed to have. In the biomedical industry, the active ingredient performs the intended chemistry or biochemistry in the body inducing the therapeutic or cleaning response. The purpose of APIs is to cause pharmacological activity or other direct effect in the diagnosis, mitigation, treatment, cure, or prevention of disease or to affect the structure and function of the human body or other animals.
Pharmaceutical technologists are predominantly occupied with the production of various dosage forms, such as tablets, pastilles or dragees, to which the desired active pharmaceutical ingredients are added. Drug formulations often contain the active ingredient mixed with a carrier or coating for easier ingestion, timed or targeted release, and different flavors and colors to make the medicine taste more pleasant. Today, different types of nano-particles are being used to encapsulate the drugs active ingredients thus reducing required doses and improving organ and tissue specificity.
LGM Pharma believes that quality assurance is key. Our number one priority is to provide the highest quality active pharmaceutical ingredients to our customers. Our manufacturing partners are fully compliant by following strict cGMP guidelines, and are regulated by leading authorities such as WHO, EDQM, TGA, US-FDA, UK-MHRA etc.
Please contact us with your API requirements today.
Tags: Active Pharmaceutical Ingredients, api, bulk active, bulk drug substance, pharma blog, pharmaceutical ingredient
Posted in Glossary | 1 Comment »
